Sertaconazole Nitrate (Ertaczo, Dermofix, Konzert, and Zalain)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $450 | Check With Us |
| 1g | $700 | Check With Us |
| 5g | $1890 | Check With Us |
: Cat #: V14671 CAS #: 99592-39-9 Purity ≥ 98%
Description: Sertaconazole nitrate (Ertaczo, Dermofix, Konzert, and Zalain) is a topical broad-spectrum antifungal medication of the imidazole class.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 500.78 |
|---|---|
| Molecular Formula | C20H16Cl3N3O4S |
| CAS No. | 99592-39-9 |
| SMILES Code | C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl.[N+](=O)(O)[O-] |
| Synonyms | Dermofix; Ertaczo; Zalain; Dermoseptic; Ginedermofix; Mykosert; sertaconazole; Zalain |
| Protocol | In Vitro | Sertaconazole nitrate (1, 2 µg/mL; 6, 8, or 24 h) increases a twofold release of PGE2 via COX-2 in keratinocytes, which is dependent on p38 activation |
|---|---|---|
| In Vivo | Sertaconazole nitrate (1% (w/v); apply to the left ear, once) suppresses of TPA-induced ear edema CD-1 mice | |
| Animal model | CD-1 mice (TPA-induced ear edema model) | |
| Dosages | 1% (w/v) | |
| Administration | Apply to the left ear, once. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9969 mL | 9.9844 mL | 19.9688 mL | 39.9377 mL |
| 5mM | 0.3994 mL | 1.9969 mL | 3.9938 mL | 7.9875 mL |
| 10mM | 0.1997 mL | 0.9984 mL | 1.9969 mL | 3.9938 mL |
| 20mM | 0.0998 mL | 0.4992 mL | 0.9984 mL | 1.9969 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.