Secnidazole
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $300 | Check With Us |
| 20g | $450 | Check With Us |
| 50g | $780 | Check With Us |
: Cat #: V13932 CAS #: 3366-95-8 Purity ≥ 99%
Description: Secnidazole (SYM 1219; SYM1219; SYM-1219; PM-185184, RP-14539; Solosec; Flagentyl) is a potent nitroimidazole anti-infective drug approved for the treatment of bacterial vaginosis in adult women.
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- Related Biological Data
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| Molecular Weight (MW) | 185.18 |
|---|---|
| Molecular Formula | C7H11N3O3 |
| CAS No. | 3366-95-8 |
| Synonyms | SYM 1219; SYM1219; SYM-1219; PM 185184, RP 14539; PM185184, RP14539 |
| Protocol | In Vitro | Secnidazole (10 μL; 20 h; the secnidazole solution was two-fold serially diluted using Mueller–Hinton broth to obtain dilutions ranging from 80 to 0.3125 mg/mL) inhibits S.marcescens growth with a MIC50 value of 10 mg/mL |
|---|---|---|
| In Vivo | Secnidazole (100 μL; ip.; for 5 days) has protective activity against S.marcescens pathogenesis and can diminish its pathogenesis in mice | |
| Animal model | Female healthy albino mice | |
| Dosages | 100 μL | |
| Administration | 100 μL; ip.; for 5 days |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 5.4002 mL | 27.0008 mL | 54.0015 mL | 108.0030 mL |
| 5mM | 1.0800 mL | 5.4002 mL | 10.8003 mL | 21.6006 mL |
| 10mM | 0.5400 mL | 2.7001 mL | 5.4002 mL | 10.8003 mL |
| 20mM | 0.2700 mL | 1.3500 mL | 2.7001 mL | 5.4002 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.