This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 5mg | $400 | 3-6 Days |
| 10mg | $580 | 3-6 Days |
| 25mg | $980 | 3-6 Days |
| 50mg | $1380 | 3-6 Days |
| 100mg | $1980 | 3-6 Days |
| 250mg | $3200 | 3-6 Days |
: Cat #: V4670 CAS #: 217963-18-3 Purity ≥ 98%
Description: SCH00013 is a novel and potent Ca2+ sensitizer that elicits a moderate positive inotropic effect without significant alteration of Ca2+ transients. As a cardiotonic agent, SCH00013 primarily acts via an increase in myofibrillar Ca++ sensitivity, with a significant Ca(2+)sensitizing effect at pH 7.2 to 7.4. SCH00013 does not have a positive chronotropic effect and has a weak PDE III inhibitory action and class III antiarrhythmic action. SCH00013 prolonged the survival in a animal heart failure model with genetic cardiomyopathy. The oral bioavailability of SCH00013 is high and equivalent to that via intravenous administration. The unique pharmacological profiles of SCH00013 imply that this agent may be potentially beneficial for pharmacotherapy of contractile dysfunction in congestive heart failure.
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Formula | C₁₈H₂₀N₄O₂ |
|---|---|
| CAS No. | 217963-18-3 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.