SCH-58261
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1250 | Check With Us |
| 500mg | $1850 | Check With Us |
| 1g | $2775 | Check With Us |
: Cat #: V2917 CAS #: 160098-96-4 Purity ≥ 98%
Description: SCH-58261 (SCH58261; SCH 58261) is a novel, potent, selective and competitive antagonist of the adenosine A2A receptor with immunomodulatory and neuroprotective effects.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 345.36 |
|---|---|
| Molecular Formula | C18H15N7O |
| CAS No. | 160098-96-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 69 mg/mL (199.79 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: N/A | |
| Solubility In Vivo | Chemical Name: 2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine InChi Key: UTLPKQYUXOEJIL-UHFFFAOYSA-N InChi Code: InChI=1S/C18H15N7O/c19-18-22-16-13(11-20-24(16)9-8-12-5-2-1-3-6-12)17-21-15(23-25(17)18)14-7-4-10-26-14/h1-7,10-11H,8-9H2,(H2,19,22) SMILES Code: NC1=NC(N(CCC2=CC=CC=C2)N=C3)=C3C4=NC(C5=CC=CO5)=NN14 |
| Synonyms | SCH58261; SCH 58261; SCH-58261 |
| Protocol | In Vitro | SCH58261 (25 μM; 72 hours) can inhibit the growth of CAF cells |
|---|---|---|
| In Vivo | SCH 58261 (2 mg/kg; i.p.; daily; for 20 days) causes a decrease in the tumor burden in a NSCLC mouse model | |
| Animal model | 4‒6 weeks old athymic nude mice (NCI) with PC9 cells xenograft | |
| Dosages | 2 mg/kg | |
| Administration | Intraperitoneal injection; daily; for 20 days |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.8955 mL | 14.4776 mL | 28.9553 mL | 57.9106 mL |
| 5mM | 0.5791 mL | 2.8955 mL | 5.7911 mL | 11.5821 mL |
| 10mM | 0.2896 mL | 1.4478 mL | 2.8955 mL | 5.7911 mL |
| 20mM | 0.1448 mL | 0.7239 mL | 1.4478 mL | 2.8955 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.