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| Size | Price | Stock |
|---|---|---|
| 10mg | $100 | In Stock |
| 25mg | $180 | In Stock |
| 50mg | $320 | In Stock |
| 100mg | $520 | In Stock |
| 250mg | $950 | In Stock |
| 500mg | $1450 | In Stock |
| 1g | $2250 | In Stock |
: Cat #: V2164 CAS #: 218136-59-5 Purity ≥ 98%
Description: SC-26196 is a novel, potent and orally bioactive D6D (Delta6 desaturase) inhibitor with IC50 of 0.2 µM in a rat liver microsomal assay. It completely blocks the conversion of linoleic acid to arachidonic acid (AA). SC-26196 inhibited the desaturation of 2 microM [1-14C] 18:2n-6 by 87-95% in cultured human skin fibroblasts, coronary artery smooth muscle cells, and astrocytes. By contrast, SC-26196 did not affect the conversion of [1-14C]20:3n-6 to 20:4 in the fibroblasts, demonstrating that it is selective for delta6-desaturase.
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| Molecular Weight (MW) | 423.564 |
|---|---|
| CAS No. | 218136-59-5 |
| SMILES Code | N#CC(C1=CC=CC=C1)(C2=CC=CC=C2)CCCN3CCN(/N=C/C4=CN=CC=C4)CC3 |
| Synonyms | SC 26196; SC26196; SC-26196 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3609 mL | 11.8046 mL | 23.6092 mL | 47.2184 mL |
| 5mM | 0.4722 mL | 2.3609 mL | 4.7218 mL | 9.4437 mL |
| 10mM | 0.2361 mL | 1.1805 mL | 2.3609 mL | 4.7218 mL |
| 20mM | 0.1180 mL | 0.5902 mL | 1.1805 mL | 2.3609 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.