SB-3CT
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1050 | Check With Us |
| 500mg | $1650 | Check With Us |
| 1g | $2475 | Check With Us |
: Cat #: V0740 CAS #: 292605-14-2 Purity ≥ 98%
Description: SB-3CT (SB 3CT) is a non-selective and covalent inhibitor of gelatinases/matrix metalloproteinase (MMP) with potential antineoplastic activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 306.40 |
|---|---|
| Molecular Formula | C15H14O3S2 |
| CAS No. | 292605-14-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 61 mg/mL (199.1 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 10 mg/mL (32.6 mM) | |
| Solubility In Vivo | 4% DMSO+corn oil: 10 mg/mL |
| SMILES Code | O=S(CC1SC1)(C2=CC=C(OC3=CC=CC=C3)C=C2)=O |
| Synonyms | SB3CT; SB3-CT; SB-3CT; |
| Protocol | In Vitro | SB-3CT has shown efficacy in an animal model of severe traumatic brain injury (TBI). SB-3CT inhibits MMP-9 with an inhibition constant Ki of 400±15 nM. |
|---|---|---|
| In Vivo | SB-3CT (i.p.; 50 mg/kg; every other day; five weeks) inhibits intraosseous growth of human PC3 cells within the marrow of human fetal femur fragments previously implanted in SCID mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.2637 mL | 16.3185 mL | 32.6371 mL | 65.2742 mL |
| 5mM | 0.6527 mL | 3.2637 mL | 6.5274 mL | 13.0548 mL |
| 10mM | 0.3264 mL | 1.6319 mL | 3.2637 mL | 6.5274 mL |
| 20mM | 0.1632 mL | 0.8159 mL | 1.6319 mL | 3.2637 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.