Sapropterin HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $1100 | Check With Us |
| 5g | $3200 | Check With Us |
| 10g | $4800 | Check With Us |
: Cat #: V3394 CAS #: 69056-38-8 (HCl) Purity ≥ 99%
Description: Sapropterin(also known as Tetrahydrobiopterin,Kuvan or sapropterin ), is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 314.17 |
|---|---|
| Molecular Formula | C9H17Cl2N5O3 |
| CAS No. | 69056-38-8 (HCl) |
| SMILES Code | O=C1N=C(N)NC2=C1N[C@@H]([C@@H](O)[C@@H](O)C)CN2.[H]Cl.[H]Cl |
| Synonyms | Sapropterin HCl; BioMarin T 1401; THB; BPH4; 6R-BH4; Tetrahydrobiopterin, sapropterin; Biopten; SN0588; SUN-0588; Tetrahydro-6-biopterin; Dapropterin; Phenoptin; trade name Kuvan |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.1830 mL | 15.9150 mL | 31.8299 mL | 63.6598 mL |
| 5mM | 0.6366 mL | 3.1830 mL | 6.3660 mL | 12.7320 mL |
| 10mM | 0.3183 mL | 1.5915 mL | 3.1830 mL | 6.3660 mL |
| 20mM | 0.1591 mL | 0.7957 mL | 1.5915 mL | 3.1830 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.