S0859
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1100 | Check With Us |
| 500mg | $1800 | Check With Us |
| 1g | $2700 | Check With Us |
: Cat #: V2877 CAS #: 1019331-10-2 Purity ≥ 99%
Description: S0859 (S-0859) is an N-cyanosulphonamide compound acting as a novel, selective, high-affinity generic inhibitor of NBC [(Na(+)-coupled HCO(3)(-) transporters].
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- Physicochemical and Storage Information
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- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 530.04 |
|---|---|
| Molecular Formula | C29H24ClN3O3S |
| CAS No. | 1019331-10-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 10 mMr |
| Water: NAr | |
| Ethanol: NA | |
| SMILES Code | O=C(N(CC1=CC=C(C2=CC=CC=C2S(=O)(NC#N)=O)C=C1)CC3=CC=C(C)C=C3)C4=CC=CC=C4Cl |
| Synonyms | S0859; S 0859; S-0859. |
| Protocol | In Vitro | Treatment with NBC inhibitor S0859 significantly increased caspase-3 activity and elevated the number of apoptotic EC. S0859 is potentially important for probing the transporter's functional role in heart and other tissues |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8867 mL | 9.4333 mL | 18.8665 mL | 37.7330 mL |
| 5mM | 0.3773 mL | 1.8867 mL | 3.7733 mL | 7.5466 mL |
| 10mM | 0.1887 mL | 0.9433 mL | 1.8867 mL | 3.7733 mL |
| 20mM | 0.0943 mL | 0.4717 mL | 0.9433 mL | 1.8867 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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The dilution calculator equation
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.