(S)-IDO1-IN-5

This product is for research use only, not for human use. We do not sell to patients.

(S)-IDO1-IN-5
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Size Price Stock
5mg$190To Be Confirmed
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Cat #: V40362 CAS #: 2166616-76-6 Purity ≥ 99%

Description: (S)-LY-3381916 ((S)-IDO1-IN-5; Example 1B) is an active S-isomer of LY-3381916 and binds IDOL with IC50 of less than 1.5 µM. LY-3381916 is a potent, selective, BBB (blood-brain barrier) permeable/penetrable IDO1 inhibitor that binds to heme-deficient apo-IDO1 but cannot bind to mature heme-containing IDO1.

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Molecular Weight (MW)396.454609632492
Molecular FormulaC23H25FN2O3
CAS No.2166616-76-6
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Synonyms(S)IDO1IN5 (S) IDO1 IN 5
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5224 mL12.6118 mL25.2236 mL50.4471 mL
5mM0.5045 mL2.5224 mL5.0447 mL10.0894 mL
10mM0.2522 mL1.2612 mL2.5224 mL5.0447 mL
20mM0.1261 mL0.6306 mL1.2612 mL2.5224 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
V1
 
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C2
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.