S-Gboxin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $750 | To Be Confirmed |
| 250mg | $1200 | To Be Confirmed |
| 500mg | $1800 | To Be Confirmed |
: Cat #: V4224 CAS #: 2101317-21-7 (iodide) Purity ≥ 98%
Description: S-Gboxin is an analogue of Gboxin with anticancer activity by potently inhibiting growth of mouse and human glioblastoma (GBM) (IC50 = 470 nM).
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 600.45 |
|---|---|
| Molecular Formula | C27H32F3IN2O2 |
| CAS No. | 2101317-21-7 (iodide) |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | FC(C1=CC(C2=[N+](CC(O[C@H]3[C@H](C(C)C)CC[C@@H](C)C3)=O)C4=CC=CC=C4N2C)=CC=C1)(F)F.[I-] |
| Synonyms | S-Gboxin; S Gboxin |
| Protocol | In Vivo | S-Gboxin retains excellent metabolic stability, enhanced plasma stability, and PK-properties suitable for in vivo studies. S-Gboxin (10 mg/kg/day; intraperitoneally) inhibits glioblastoma (GBM) growth in vivo. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6654 mL | 8.3271 mL | 16.6542 mL | 33.3084 mL |
| 5mM | 0.3331 mL | 1.6654 mL | 3.3308 mL | 6.6617 mL |
| 10mM | 0.1665 mL | 0.8327 mL | 1.6654 mL | 3.3308 mL |
| 20mM | 0.0833 mL | 0.4164 mL | 0.8327 mL | 1.6654 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.