S-26131

This product is for research use only, not for human use. We do not sell to patients.

S-26131
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$700To Be Confirmed
250mg$1350To Be Confirmed
500mg$2025To Be Confirmed

Cat #: V5199 CAS #: 296280-56-3 Purity ≥ 98%

Description: S-26131 (S26131) is a novel and selective MT1 and MT2 antagonist, with Ki values of 0.5 and 112 nM for MT1 and MT2, respectively.

References: Descamps-François C, et al. Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands. J Med Chem. 2003 Mar 27;46(7):1127-9.

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Product Promise

Promise
Molecular Weight (MW)498.61
Molecular FormulaC31H34N2O4
CAS No.296280-56-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
ProtocolIn VitroS26131 behaves as an antagonist on MT1 and MT2 receptors with KB values of 5.32 and 143 nM, respectively
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0056 mL10.0279 mL20.0558 mL40.1115 mL
5mM0.4011 mL2.0056 mL4.0112 mL8.0223 mL
10mM0.2006 mL1.0028 mL2.0056 mL4.0112 mL
20mM0.1003 mL0.5014 mL1.0028 mL2.0056 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.