RUVBL1/2 ATPase-IN-1

This product is for research use only, not for human use. We do not sell to patients.

RUVBL1/2 ATPase-IN-1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$3103-6 Days
email: [email protected]        [email protected]

Cat #: V48070 CAS #: 423128-55-6 Purity ≥ 99%

Description: RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and specific RUVBL1/2 ATPase inhibitor (antagonist) with IC50s of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases related to a variety of cellular activities), which are highly related to the progression of cancer. RUVBL1/2 ATPase-IN-1 may be used for studying cancer diseases.

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Molecular Weight (MW)507.55
Molecular FormulaC28H28F3N5O
CAS No.423128-55-6
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: This product requires protection from light (avoid light exposure) during transportation and storage.

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9702 mL9.8512 mL19.7025 mL39.4050 mL
5mM0.3940 mL1.9702 mL3.9405 mL7.8810 mL
10mM0.1970 mL0.9851 mL1.9702 mL3.9405 mL
20mM0.0985 mL0.4926 mL0.9851 mL1.9702 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.