RS-127445 maleate

This product is for research use only, not for human use. We do not sell to patients.

RS-127445 maleate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10mg$1703-6 Days
25mg$3103-6 Days
50mg$5003-6 Days
100mg$7603-6 Days
250mg$10603-6 Days
email: [email protected]        [email protected]

Cat #: V2447 CAS #: 199864-88-5 Purity ≥ 99%

Description: RS 127445 maleate is a novel,selective, high affinity and orally bioavailable antagonist of 5-HT2B receptor ( pKi = 9.5).

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Molecular Weight (MW)397.40
Molecular FormulaC17H16FN3.C4H4O4
CAS No.199864-88-5
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsRS-127445 maleateRS 127445 maleateRS127445 maleate
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5164 mL12.5818 mL25.1636 mL50.3271 mL
5mM0.5033 mL2.5164 mL5.0327 mL10.0654 mL
10mM0.2516 mL1.2582 mL2.5164 mL5.0327 mL
20mM0.1258 mL0.6291 mL1.2582 mL2.5164 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.