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(+/-)-Roscovitine

This product is for research use only, not for human use. We do not sell to patients.

(+/-)-Roscovitine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$803-6 Days
10mg$1253-6 Days
25mg$2003-6 Days
50mg$3003-6 Days
100mg$4503-6 Days
250mg$7003-6 Days
email: [email protected]        [email protected]

Cat #: V41328 CAS #: 186692-44-4 Purity ≥ 99%

Description: (+/-)-Roscovitine is a racemate. The R-isomer is Seliciclib (Roscovitine, CYC202) which is a novel, potent, selective and orally bioavailable small-molecule CDK inhibitor with IC50 of 0.65 μM, 0.7 μM and 0.16 μM for Cdc2, CDK2 and CDK5 in cell-free assays.

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Molecular Formula354.45
CAS No.186692-44-4
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.