Riboflavin Tetrabutyrate

This product is for research use only, not for human use. We do not sell to patients.

Riboflavin Tetrabutyrate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50g$450Check With Us
100g$750Check With Us
200g$1125Check With Us

Cat #: V29430 CAS #: 752-56-7 Purity ≥ 99%

Description: Riboflavin Tetrabutyrate is a lipophilic analogue of Riboflavin (vitamin B2), which is a vitamin B and an important nutrient that plays a key role in maintaining health in humans and other animals.

References: Tahara K, et al. Effect of riboflavin and riboflavin 2',3',4',5'-tetrabutyrate on rat liver microsomallipid peroxidation. J Nutr Sci Vitaminol (Tokyo). 1974;20(2):81-8.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)656.72
Molecular FormulaC33H44N4O10
CAS No.752-56-7
SMILES CodeO=C([C@H](C)C[C@@](C)(OC)[C@H](O[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O)[C@@H](C)C([C@@H](C)C(O[C@H](CC)[C@@]2(C)O3)=O)=O)[C@H](C)[C@@]2([H])N(CCCCN4C=C(C5=CC=CN=C5)N=C4)C3=O
SynonymsTelithromycin; HMR-3647; HMR 3647; HMR3647; RU-66647; RU 66647; RU66647
ProtocolIn VitroRiboflavin Tetrabutyrate inhibits oxygen uptake by lipid peroxidation. Riboflavin Tetrabutyrate is suppressive against both NADPH-coupled and ascorbate-induced microsomal lipid peroxidation. Riboflavin Tetrabutyrate seems to exhibit its antioxidative action at or after the hydrogen atom is abstracted as a free radical from an active methylene group of polyunsaturated fatty acids during the process of enzymic oxidation-reduction reaction.
In VivoRiboflavin Tetrabutyrate might improve the metabolism of lipids in patients suffering from atherosclerosis, diabetes, fatty liver and so on through the inhibition of lipid peroxide, resulting in the decrease of the elevated serum lipid.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.5227 mL7.6136 mL15.2272 mL30.4544 mL
5mM0.3045 mL1.5227 mL3.0454 mL6.0909 mL
10mM0.1523 mL0.7614 mL1.5227 mL3.0454 mL
20mM0.0761 mL0.3807 mL0.7614 mL1.5227 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.