Ribavirin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50g | $350 | Check With Us |
| 100g | $525 | Check With Us |
| 200g | $785 | Check With Us |
: Cat #: V13768 CAS #: 36791-04-5 Purity ≥ 99%
Description: Ribavirin is a potent and broad spectrum anti-viral drug and nucleoside which acts as an inhibitor of inosine monophosphate dehydrogenase as well as a Viral RNA polymerase inhibitor.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 244.2047 |
|---|---|
| Molecular Formula | C8H12N4O5 |
| CAS No. | 36791-04-5 |
| Synonyms | Ribavirin, Copegus, Rebetol, Virazole, ICN-1229 |
| Protocol | In Vitro | Ribavirin (ICN-1229) is active against DENV, EC in A549 cells50 At 3 μM, the combination of CM-10-18 and Ribavirin (ICN-1229) is reducing viral replication |
|---|---|---|
| In Vivo | Ribavirin (40 mg/kg, po) significantly increased the antiviral efficacy of CM-10-18 in mice. Ribavirin (ICN-1229) inhibits DENV virus infection in cultured cells, but monotherapy is ineffective in reducing viremia |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.0949 mL | 20.4746 mL | 40.9493 mL | 81.8985 mL |
| 5mM | 0.8190 mL | 4.0949 mL | 8.1899 mL | 16.3797 mL |
| 10mM | 0.4095 mL | 2.0475 mL | 4.0949 mL | 8.1899 mL |
| 20mM | 0.2047 mL | 1.0237 mL | 2.0475 mL | 4.0949 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.