Regadenoson (CVT-3146)

This product is for research use only, not for human use. We do not sell to patients.

Regadenoson (CVT-3146)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$625Check With Us
500mg$990Check With Us
1g$1485Check With Us

Cat #: V5091 CAS #: 313348-27-5 Purity ≥ 98%

Description: Regadenoson (CVT3146), a novel and potent A2A adenosine receptor agonist, is a coronary vasodilator that is commonly used in pharmacologic stress testing.

References: Trochu JN, et al. Selective A2A adenosine receptor agonist as a coronary vasodilator in conscious dogs: potential for use in myocardial perfusion imaging. J Cardiovasc Pharmacol. 2003 Jan;41(1):132-9. 

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Product Promise

Promise
Molecular Weight (MW)390.35
Molecular FormulaC15H18N8O5
CAS No.313348-27-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
ProtocolIn VivoRegadenoson (0.1, 0.175, 0.25, 0.5, 1.0, 2.5, 5 µg/kg; p.i.v.; single) increases coronary blood flow (CBF) and decreases in mean coronary resistance in a dose-dependent manner, in awake dogs
FormulationMongrel dogs (23-27 kg)
Dosages0.1, 0.175, 0.25, 0.5, 1.0, 2.5, 5 µg/kg
AdministrationPeripheral intravenous injection; single.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5618 mL12.8090 mL25.6180 mL51.2361 mL
5mM0.5124 mL2.5618 mL5.1236 mL10.2472 mL
10mM0.2562 mL1.2809 mL2.5618 mL5.1236 mL
20mM0.1281 mL0.6405 mL1.2809 mL2.5618 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.