Regadenoson (CVT-3146)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
250mg | $625 | Check With Us |
500mg | $990 | Check With Us |
1g | $1485 | Check With Us |
Cat #: V5091 CAS #: 313348-27-5 Purity ≥ 98%
Description: Regadenoson (CVT3146), a novel and potent A2A adenosine receptor agonist, is a coronary vasodilator that is commonly used in pharmacologic stress testing.
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- Physicochemical and Storage Information
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- Related Biological Data
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Molecular Weight (MW) | 390.35 |
---|---|
Molecular Formula | C15H18N8O5 |
CAS No. | 313348-27-5 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent |
Protocol | In Vivo | Regadenoson (0.1, 0.175, 0.25, 0.5, 1.0, 2.5, 5 µg/kg; p.i.v.; single) increases coronary blood flow (CBF) and decreases in mean coronary resistance in a dose-dependent manner, in awake dogs |
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Formulation | Mongrel dogs (23-27 kg) | |
Dosages | 0.1, 0.175, 0.25, 0.5, 1.0, 2.5, 5 µg/kg | |
Administration | Peripheral intravenous injection; single. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.5618 mL | 12.8090 mL | 25.6180 mL | 51.2361 mL |
5mM | 0.5124 mL | 2.5618 mL | 5.1236 mL | 10.2472 mL |
10mM | 0.2562 mL | 1.2809 mL | 2.5618 mL | 5.1236 mL |
20mM | 0.1281 mL | 0.6405 mL | 1.2809 mL | 2.5618 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.