Ranitidine HCl

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5g	$350	Check With Us
10g	$550	Check With Us
20g	$825	Check With Us

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Cat #: V1211 CAS #: 66357-59-3 Purity ≥ 98%

Description: Ranitidine HCl (ZANTAC; AH-19065; AH 19065; Tanidina; Toriol; Fendibina; Gastridina; Sostril; Zantic; Ranisen), the hydrochloride salt of Ranitidine, is a histamine H2-receptor antagonist with an IC50 of 3.3 ± 1.4 uM.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	350.86
Molecular Formula	C13H22N4O3S.HCl
CAS No.	66357-59-3
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 70 mg/mL (199.5 mM)r
	Water: 70 mg/mL (199.5 mM)r
	Ethanol:<1 mg/mL
Solubility In Vivo	Chemical Name: (E)-N-(2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)-N'-methyl-2-nitroethene-1,1-diamine hydrochloride InChi Key: GGWBHVILAJZWKJ-KJEVSKRMSA-N InChi Code: InChI=1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;/h4-5,9,14-15H,6-8,10H2,1-3H3;1H/b13-9+; SMILES Code: CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C.Cl
Synonyms	AH19065; Ranitidine Hydrochloride; ZANTAC; AH-19065; AH 19065; Tanidina; Toriol; Fendibina; Gastridina; Sostril; Zantic; Ranisen; Ranitidine HCl

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.8501 mL	14.2507 mL	28.5014 mL	57.0028 mL
5mM	0.5700 mL	2.8501 mL	5.7003 mL	11.4006 mL
10mM	0.2850 mL	1.4251 mL	2.8501 mL	5.7003 mL
20mM	0.1425 mL	0.7125 mL	1.4251 mL	2.8501 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.