Ralmitaront (WHO-11130; RO-6889450; RG-7906)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
50mg	$1950	To Be Confirmed
100mg	$2925	To Be Confirmed
200mg	$4385	To Be Confirmed

: [email protected] [email protected]

Cat #: V41800 CAS #: 2133417-13-5 Purity ≥ 99%

Description: Ralmitaront (WHO-11130; RO-6889450; RG-7906) is a novel and orally bioactive partial agonist of TAAR1 (trace amine-associated receptor 1) and a neuroleptic agent that may be used for the treatment of neuro-related diseases, such as schizophrenia (SCZ), schizoaffective disorder, and negative symptoms.

References: Linda S Brady, et al. Redirecting the revolution: new developments in drug development for psychiatry. Expert Opin Drug Discov. 2019 Dec;14(12):1213-1219.

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Molecular Weight (MW)	314.38
Molecular Formula	C17H22N4O2
CAS No.	2133417-13-5

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.1809 mL	15.9043 mL	31.8086 mL	63.6173 mL
5mM	0.6362 mL	3.1809 mL	6.3617 mL	12.7235 mL
10mM	0.3181 mL	1.5904 mL	3.1809 mL	6.3617 mL
20mM	0.1590 mL	0.7952 mL	1.5904 mL	3.1809 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.