Rabeximod

This product is for research use only, not for human use. We do not sell to patients.

Rabeximod
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Cat #: V5490 CAS #: 872178-65-9 Purity ≥ 99%

Description: Rabeximod (ROB803; ROB-803) is a novel and potent immunomodulator for the treatment of moderate or severe active rheumatoid arthritis. It is currently undergoing phase II clinical trials. It reduced the arthritis by preventing the TLR2 and TLR4 mediated inflammatory cells activation.

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Molecular Weight (MW)409.918
Molecular FormulaC22H24ClN5O
CAS No.872178-65-9
SynonymsROB-803; ROB-803; ROB-803; Rabeximod
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4395 mL12.1976 mL24.3951 mL48.7902 mL
5mM0.4879 mL2.4395 mL4.8790 mL9.7580 mL
10mM0.2440 mL1.2198 mL2.4395 mL4.8790 mL
20mM0.1220 mL0.6099 mL1.2198 mL2.4395 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.