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Rabeprazole Sodium (LY307640 sodium)

This product is for research use only, not for human use. We do not sell to patients.

Rabeprazole Sodium (LY307640 sodium)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$430To Be Confirmed
1g$645To Be Confirmed
5g$1740To Be Confirmed

Cat #: V4894 CAS #: 117976-90-6 Purity ≥ 98%

Description: Rabeprazole sodium (LY-307640 sodium) is a novel, potent and 2nd-generation proton pump inhibitor (PPI) that is used as an antiulcer drug.

References: Lulu Yao, et al. Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity. Nat Commun. 2018 Oct 1;9(1):4000.

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Molecular Weight (MW)343.42
Molecular FormulaC18H18FN3OS
CAS No.117976-90-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
ProtocolIn VitroA reciprocal allosteric interaction between the GNE-8324 and glutamate binding sites at GluN2A NMDARs such that binding of glutamate enhances binding of GNE-8324 and vice versa. GNE-8324 selectively potentiates GluN2A subunit-containing NMDARs. As a consequence, GNE-8324 potentiation is highly dependent on glutamate site occupancy with enhanced GNE-8324 binding to glutamate-bound NMDARs compared to glutamate-free NMDARs
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9119 mL14.5594 mL29.1189 mL58.2377 mL
5mM0.5824 mL2.9119 mL5.8238 mL11.6475 mL
10mM0.2912 mL1.4559 mL2.9119 mL5.8238 mL
20mM0.1456 mL0.7280 mL1.4559 mL2.9119 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.