R306465 | CAS 604769-01-9

R306465

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5mg	$150	To Be Confirmed
10mg	$250	To Be Confirmed
25mg	$450	To Be Confirmed
50mg	$800	To Be Confirmed
100mg	$1350	To Be Confirmed

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Cat #: V5627 CAS #: 604769-01-9 Purity ≥ 99%

Description: R306465, formerly known as JNJ-16241199, is a novel and potent inhibitor of hydroxamate-based histone deacetylase (HDAC) with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical models.

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Molecular Weight (MW)	413.45026
Molecular Formula	C19H19N5O4S
CAS No.	604769-01-9
Synonyms	R 306465; JNJ-16241199; R306465; JNJ16241199; R-306465

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.4187 mL	12.0934 mL	24.1867 mL	48.3734 mL
5mM	0.4837 mL	2.4187 mL	4.8373 mL	9.6747 mL
10mM	0.2419 mL	1.2093 mL	2.4187 mL	4.8373 mL
20mM	0.1209 mL	0.6047 mL	1.2093 mL	2.4187 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.