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Quinine HCl Dihydrate

This product is for research use only, not for human use. We do not sell to patients.

Quinine HCl Dihydrate
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Size Price Stock
25g$180Check With Us
50g$330Check With Us
100g$495Check With Us

Cat #: V0309 CAS #: 6119-47-7 Purity ≥ 98%

Description: Quinine HCl dihydrate (Quinine hydrochloride dihydrate) is a novel, potent naturally occuring compound with a variety of biological activities such as anti-malarial, antipyretic, analgesic , anti-inflammatory properties.

References: Jhanwar, Deepika,et al. Chemoprevention of DMBA induced skin carcinogenesis in swiss albino mice by quinine sulfate.(2016): 2636-2640.

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Molecular Weight (MW)396.91
Molecular FormulaC20H24N2O2.HCl.2H2O
CAS No.6119-47-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 79 mg/mL (199.0 mM)r
Water: 43 mg/mL (108.33 mMr
Ethanol: 79 mg/mL (199.0 mM)
Synonyms6'-Methoxycinchonidine; Quinine; Chinin; Chininum; (8S,9R)-Quinine; Qualaquin; Odan Brand of Quinine Sulfate; Plough Brand of Quinine Sulfate; Prosana Brand of Quinine Bisulfate; Quinamm; Quinbisan; Quinbisul; Quindan; Quinine HCl; Quinine hydrochloride dihydrate;
ProtocolIn VitroQuinine hydrochloride dihydrate (oral gavage, 12 or 15 mg/kg, every week, 16 weeks) has some tumor suppressing effect on skin cancer in Swiss albino mice
Animal modelSwiss albino mice 7-8-weeks
AdministrationOral gavage; every week; 16 weeks
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5195 mL12.5973 mL25.1946 mL50.3893 mL
5mM0.5039 mL2.5195 mL5.0389 mL10.0779 mL
10mM0.2519 mL1.2597 mL2.5195 mL5.0389 mL
20mM0.1260 mL0.6299 mL1.2597 mL2.5195 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.