Quinine HCl Dihydrate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
25g | $180 | Check With Us |
50g | $330 | Check With Us |
100g | $495 | Check With Us |
Cat #: V0309 CAS #: 6119-47-7 Purity ≥ 98%
Description: Quinine HCl dihydrate (Quinine hydrochloride dihydrate) is a novel, potent naturally occuring compound with a variety of biological activities such as anti-malarial, antipyretic, analgesic , anti-inflammatory properties.
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- Related Biological Data
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Molecular Weight (MW) | 396.91 |
---|---|
Molecular Formula | C20H24N2O2.HCl.2H2O |
CAS No. | 6119-47-7 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 79 mg/mL (199.0 mM)r |
Water: 43 mg/mL (108.33 mMr | |
Ethanol: 79 mg/mL (199.0 mM) | |
Synonyms | 6'-Methoxycinchonidine; Quinine; Chinin; Chininum; (8S,9R)-Quinine; Qualaquin; Odan Brand of Quinine Sulfate; Plough Brand of Quinine Sulfate; Prosana Brand of Quinine Bisulfate; Quinamm; Quinbisan; Quinbisul; Quindan; Quinine HCl; Quinine hydrochloride dihydrate; |
Protocol | In Vitro | Quinine hydrochloride dihydrate (oral gavage, 12 or 15 mg/kg, every week, 16 weeks) has some tumor suppressing effect on skin cancer in Swiss albino mice |
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Animal model | Swiss albino mice 7-8-weeks | |
Administration | Oral gavage; every week; 16 weeks |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.5195 mL | 12.5973 mL | 25.1946 mL | 50.3893 mL |
5mM | 0.5039 mL | 2.5195 mL | 5.0389 mL | 10.0779 mL |
10mM | 0.2519 mL | 1.2597 mL | 2.5195 mL | 5.0389 mL |
20mM | 0.1260 mL | 0.6299 mL | 1.2597 mL | 2.5195 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.