Quetiapine sulfoxide dihydrochloride

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V30898 CAS #: 329218-11-3 Purity ≥ 99%

Description: Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide 2HCl) is a major metabolite of Quetiapinem, which is a 2nd-generation antipsychotic acting as a 5-HT receptor agonist and a dopamine receptor antagonist.

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Molecular Weight (MW)	472.43
Molecular Formula	C₂₁H₂₇Cl₂N₃O₃S
CAS No.	329218-11-3
Synonyms	Quetiapine S-oxide dihydrochloride

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.1167 mL	10.5836 mL	21.1672 mL	42.3343 mL
5mM	0.4233 mL	2.1167 mL	4.2334 mL	8.4669 mL
10mM	0.2117 mL	1.0584 mL	2.1167 mL	4.2334 mL
20mM	0.1058 mL	0.5292 mL	1.0584 mL	2.1167 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.