PZ-128 | CAS 371131-16-7

PZ-128

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10mg	$200	To Be Confirmed
25mg	$400	To Be Confirmed
50mg	$650	To Be Confirmed
100mg	$990	To Be Confirmed

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Cat #: V13455 CAS #: 371131-16-7 Purity ≥ 99%

Description: PZ-128 (PZ128; P1pal-7) is a novel and potent PAR1 (protease-activated receptor-1) antagonist with antiplatelet, anti-metastatic, anti-angiogenic and anticancer activity and has the potential for the treatment of thrombosis. As a cell-penetrating lipopeptide pepducin, PZ-128 targets the cytoplasmic surface of PAR1 and interrupts signaling to internally-located G (PAR1-G) proteins.

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Molecular Weight (MW)	1086.47
Molecular Formula	C55H99N13O9
CAS No.	371131-16-7
Synonyms	PZ 128; PZ128

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.9204 mL	4.6021 mL	9.2041 mL	18.4082 mL
5mM	0.1841 mL	0.9204 mL	1.8408 mL	3.6816 mL
10mM	0.0920 mL	0.4602 mL	0.9204 mL	1.8408 mL
20mM	0.0460 mL	0.2301 mL	0.4602 mL	0.9204 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.