Pyrantel pamoate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
50g | $400 | Check With Us |
100g | $650 | Check With Us |
200g | $975 | Check With Us |
Cat #: V13416 CAS #: 22204-24-6 Purity ≥ 99%
Description: Pyrantel pamoate, the pamoate salt of pyrantel, is a potent antinematodal and anthelmintic agent with a broad spectrum of activities.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
Molecular Weight (MW) | 594.68 |
---|---|
Molecular Formula | C34H30N2O6S |
CAS No. | 22204-24-6 |
Protocol | In Vitro | Pyrantel pamoate (10 nM-10 µM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity |
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In Vivo | Pyrantel pamoate (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4% | |
Animal model | Male Syrian Golden hamsters (3-week-old; A. ceylanicum-infected) | |
Dosages | 10 mg/kg | |
Administration | Oral administration; single. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 1.6816 mL | 8.4079 mL | 16.8158 mL | 33.6315 mL |
5mM | 0.3363 mL | 1.6816 mL | 3.3632 mL | 6.7263 mL |
10mM | 0.1682 mL | 0.8408 mL | 1.6816 mL | 3.3632 mL |
20mM | 0.0841 mL | 0.4204 mL | 0.8408 mL | 1.6816 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.