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PUN-30119

This product is for research use only, not for human use. We do not sell to patients.

PUN-30119
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1050In Stock
250mg$1850In Stock
500mg$2775In Stock
email: [email protected]        [email protected]

Cat #: V4648 CAS #: 1801530-11-9 Purity ≥ 98%

Description: Imidazole ketone erastin (IKE) or PUN30119 is a novel, potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system Xc- and an activator of ferroptosis.

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Molecular Weight (MW)655.152
Molecular FormulaC35H35ClN6O5
CAS No.1801530-11-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C1N(C2=CC(C(CN3C=NC=C3)=O)=CC=C2OC(C)C)C(CN4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)=NC6=C1C=CC=C6
SynonymsPUN30119; PUN-30119; PUN 30119; Imidazole Ketone Erastin;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.5264 mL7.6318 mL15.2636 mL30.5273 mL
5mM0.3053 mL1.5264 mL3.0527 mL6.1055 mL
10mM0.1526 mL0.7632 mL1.5264 mL3.0527 mL
20mM0.0763 mL0.3816 mL0.7632 mL1.5264 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.