PU139

This product is for research use only, not for human use. We do not sell to patients.

PU139
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$140To Be Confirmed
10mg$230To Be Confirmed
email: [email protected]        [email protected]

Cat #: V13366 CAS #: 158093-65-3 Purity ≥ 99%

Description: PU139 is a potent pan-histone acetyltransferase (HAT) inhibitor. PU139 blocks HATs Gcn5, p300/CBP-associated factor (PCAF), CBP and p300 with IC50 of 8.39, 9.74, 2.49 and 5.35 μM respectively.

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Molecular Weight (MW)246.2594
Molecular FormulaC12H7FN2OS
CAS No.158093-65-3
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.

SynonymsPU139 PU-139 PU 139
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.0608 mL20.3038 mL40.6076 mL81.2152 mL
5mM0.8122 mL4.0608 mL8.1215 mL16.2430 mL
10mM0.4061 mL2.0304 mL4.0608 mL8.1215 mL
20mM0.2030 mL1.0152 mL2.0304 mL4.0608 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
V1
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.