Psoralen (psoralene, Ficusin, Furocoumarin)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $390 | Check With Us |
| 500mg | $650 | Check With Us |
| 1g | $975 | Check With Us |
: Cat #: V2565 CAS #: 66-97-7 Purity ≥ 98%
Description: Psoralen (psoralene, Ficusin, Furocoumarin) is a naturally occurring furocoumarin isolated from Fructus Psoraleae, it intercalates with DNA, inhibiting DNA synthesis and cell division.
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| Molecular Weight (MW) | 186.16 |
|---|---|
| Molecular Formula | C11H6O3 |
| CAS No. | 66-97-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 37 mg/mL (198.8 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| Synonyms | psoralene, Ficusin, Furocoumarin |
| Protocol | In Vitro | Psoralen (10-500 μM; 24-48 hours) inhibits cell viability in a concentration- and time-dependent manner in L02 and HepG2 cells. In L02 cells, Psoralen at 400 μM does not significantly change extracellular LDH levels, and 400 μM or 450 μM psoralen inhibits 50–60% of cell viability |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 5.3717 mL | 26.8586 mL | 53.7172 mL | 107.4345 mL |
| 5mM | 1.0743 mL | 5.3717 mL | 10.7434 mL | 21.4869 mL |
| 10mM | 0.5372 mL | 2.6859 mL | 5.3717 mL | 10.7434 mL |
| 20mM | 0.2686 mL | 1.3429 mL | 2.6859 mL | 5.3717 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.