Proxyphylline
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $200 | Check With Us |
| 2g | $350 | Check With Us |
| 5g | $530 | Check With Us |
: Cat #: V3125 CAS #: 603-00-9 Purity ≥ 98%
Description: Proxyphylline is a derivative of methylxanthine that is clinically used as a cardiac stimulant, a vasodilator and a bronchodilator.
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- Related Biological Data
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| Molecular Weight (MW) | 238.25 |
|---|---|
| Molecular Formula | C10H14N4O3 |
| CAS No. | 603-00-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: >10 mMr |
| Water:r | |
| Ethanol: | |
| SMILES Code | O=C(N1C)N(C)C2=C(N(CC(O)C)C=N2)C1=O |
| Synonyms | Monophylline, Spasmolysin |
| Protocol | In Vivo | Proxyphylline exhibits bronchodilatory effect. Proxyphylline inhibits cAMP and cGMP hydrolysis in human lung tissue. The apparent inhibition constant of proxyphylline is 0.06-0.7 mM at low cAMP concentrations and it is 1.0 mM at high cAMP concentrations |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.1973 mL | 20.9864 mL | 41.9727 mL | 83.9454 mL |
| 5mM | 0.8395 mL | 4.1973 mL | 8.3945 mL | 16.7891 mL |
| 10mM | 0.4197 mL | 2.0986 mL | 4.1973 mL | 8.3945 mL |
| 20mM | 0.2099 mL | 1.0493 mL | 2.0986 mL | 4.1973 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.