This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 5mg | $98 | 3-6 Days |
| 10mg | $150 | 3-6 Days |
| 25mg | $250 | 3-6 Days |
| 50mg | $450 | 3-6 Days |
| 100mg | $750 | 3-6 Days |
| 250mg | $1250 | 3-6 Days |
| 500mg | $1950 | 3-6 Days |
: Cat #: V4132 CAS #: 1448297-52-6 Purity ≥ 98%
Description: PROTAC-VHL-ligand or Protein degrader 1 is a novel and potent small molecule ligand for VHL (Von Hippel-Lindau), an E3 ligase which has been targeted by many PROTACs (proteolysis-targeting chimeras) degarders. Small molecule-induced protein degradation is an attractive strategy for the development of chemical probes. One method for inducing targeted protein degradation involves the use of PROTACs, heterobifunctional molecules that can recruit specific E3 ligases to a desired protein of interest. PROTACs have been successfully used to degrade numerous proteins in cells, but the peptidic E3 ligase ligands used in previous PROTACs have hindered their development into more mature chemical probes or therapeutics.
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| CAS No. | 1448297-52-6 |
|---|---|
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.