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| Size | Price | Stock |
|---|---|---|
| 1mg | $450 | To Be Confirmed |
: Cat #: V37840 CAS #: 2360533-90-8 Purity ≥ 99%
Description: PROTAC IRAK4 degrader-1 is a Cereblon-based IRAK4 PROTAC. For more details, check and find compound I-210 from the patent US20190192668A1. PROTAC IRAK4 degrader-1 acted on OCI-LY-10 cells at concentrations of 0.01, 0.1 and 1 μM, causing <20%, >20-50% and >50% IRAK4 protein degradation respectively.
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| Molecular Weight (MW) | 904.85 |
|---|---|
| Molecular Formula | C44H39F3N12O7 |
| CAS No. | 2360533-90-8 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Synonyms | PROTAC IRAK4 degrader1; PROTAC IRAK4 degrader 1 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.1052 mL | 5.5258 mL | 11.0516 mL | 22.1031 mL |
| 5mM | 0.2210 mL | 1.1052 mL | 2.2103 mL | 4.4206 mL |
| 10mM | 0.1105 mL | 0.5526 mL | 1.1052 mL | 2.2103 mL |
| 20mM | 0.0553 mL | 0.2763 mL | 0.5526 mL | 1.1052 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.