Propentofylline

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$500	Check With Us
250mg	$950	Check With Us
500mg	$1425	Check With Us

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Cat #: V13255 CAS #: 55242-55-2 Purity ≥ 99%

Description: Propentofylline (HWA285; HWA-285; HWA 285; Karsivan; Hextol; Propentophylline), a xanthine derivative, is a potent phosphodiesterase (PDE) inhibitor with potential neuroprotective activity.

References: Hudlicka O, Komarek J, Wright AJ. The effect of a xanthine derivative, 1-(5' oxohexyl)-3-methyl-7-propylxanthine (HWA 285), on heart performance and regional blood flow in dogs and rabbits. Br J Pharmacol. 1981;72(4):723-730.

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Molecular Weight (MW)	306.36
Molecular Formula	C15H22N4O3
CAS No.	55242-55-2
SMILES Code	O=C(N1CCCCC(C)=O)N(C)C2=C(N(CCC)C=N2)C1=O
Synonyms	Propentofylline; Hextol; Karsivan; Propentophylline; HWA-285; HWA 285; HWA285;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.2641 mL	16.3207 mL	32.6413 mL	65.2827 mL
5mM	0.6528 mL	3.2641 mL	6.5283 mL	13.0565 mL
10mM	0.3264 mL	1.6321 mL	3.2641 mL	6.5283 mL
20mM	0.1632 mL	0.8160 mL	1.6321 mL	3.2641 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.