MRT-68921 (MRT68921; MRT 68921) is a novel, potent and dual inhibitor of the autophagy kinase ULK1 and ULK2 with IC50s of 2.9 and 1.1 nM, respectively.

MRT-68921 HCl, the hydrochloride salt of MRT68921, is a dual inhibitor of ULK1 and ULK2 (the autophagy kinases) with potential anticancer activity.

BL-918, a racemic mixture, is a novel and potent small molecule activator of UNC-51-like kinase 1 (ULK1), inducing cytoprotective autophagy for Parkinson’s disease treatment.

LYN-1604 (LYN1604) is a potent agonist or activator of the UNC-51-like kinase 1 (ULK1) with potential antitumor activity.

SBP-7455 is a potent dual inhibitors of ULK1 and ULK2 (ULK1/2),It potently inhibited ULK1/2 enzymatic activity.

LYN-1604 HCl, the hydrochloride salt of LYN-1604, is a novel and potent activator/agonist of the UNC-51-like kinase 1 (ULK1) (EC50 = 18.94 nM) with anticancer activity.