NSC-87877 (NSC87877) is a novel, potent, cell-permeable small molecule and competitive inhibitor of SHP-1 and SHP-2 PTP (protein tyrosine phosphatase) with anticancer activity.

RMC-4550 (RMC4550) is a novel, potent, selective and allosteric inhibitor of SHP2 phosphatase with anticancer activity.

SHP099 (SHP-099), identified through HTS and structure-based drug design, is a potent, selective, orally bioavailable, and highly efficacious allosteric inhibitor of SHP2 [Src homology-2 domain containing protein tyrosine phosphatase-2] with anticancer and anti-osteoarthritis activity.

SHP099 HCl, the HCl salt of SHP-099, is an orally bioavailable, and allosteric SHP2 inhibitor with antitumor and anti-inflammatory effects.

TNO155 (TNO-155) is an inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11; IC50=11 nM) with potential anticancer activity.