RIPA-56 is a novel, highly potent, selective, and metabolically stable inhibitor of receptor-interacting protein 1 (RIP1) with an IC50 of 13 nM.

GSK583 is a highly potent and selective RIP2 kinase inhibitor with an IC50 value of 5 nM.

GSK2983559 active metabolite, formerly known as RIPK2-IN-1, is an active metabolite of GSK2983559 which is a potent and selective inhibitor of receptor interacting protein-2 (RIP2) kinase.

GSK’872 (also known as GSK2399872A, GSK872, or GSK-872) is a novel, potent and selective RIPK3 (receptor interacting protein kinase-3) inhibitor. ction to primary hepatocytes.

Necrostatin 2 R-isomer is the R-enantiomer of Necrostatin 2 (also known as Necrostatin-2, Necrostatin-2 racemate, (±)-Necrostatin-2, 7-Cl-O-Nec-1 and Nec-1s) which is a potent necroptosis inhibitor with EC50 of 50 nM.

GSK2593074A (also known as GSK’074) is a novel and potent necroptosis inhibitor with dual targeting ability to both RIP1 and RIP3.

HS-1371 is a novel, potent and ATP-competitive RIP3 (receptor-interacting protein kinase 3) inhibitor that is identified by the extensive screening of chemical libraries focused on kinases.

GSK’547 (GSK547; GSK-547) is a novel, potent and highly selective inhibitor of RIP1 (receptor-interacting serine/threonine protein kinase 1) with immunomodulatory effects.