Angeloylgomisin H is a novel and potent lignin extract
Clofibrate (Atromid-S) is a novel and potent lipid-lowering agent acting as an agonist of PPAR with EC50s of 50 μM, ∼500 μM for murine PPARα and PPARγ, and 55 μM, ∼500 μM for human PPARα and PPARγ, respectively
MA-0204 is a highly potent and selective PPARd modulator (PPARδ EC50 = 0.4 nM; PPARalpha, EC50 == 6,660 nM) that upregulates the expression of FAO genes in human renal proximal tubule cells, resulting in increased mitochondrial fatty acid oxidation.
Seladelpar (formerly MBX-8025 and RWJ-800025) is a novel, orally bioactive and selective peroxisome proliferator-activated receptor (PPAR)-δ receptor agonist with anti-cholestatic effects.
LJ570 is a PPARα/PPARγ dual agonist with EC50s of 1.05 and 0.12 μM, respectively.
AZD-9574, PARP1 inhibitor