SMI-16a (Pim1/2 Inhibitor IV) is a novel, potent, selective, cell-permeable, ATP-competitive Pim kinase inhibitor with IC50 values of 0.15, 0.02 and 48 μM for Pim1, Pim2 and PC3 cells, respectively.

INCB053914 is a novel, potent, selective, and ATP-competitive small molecule pan-inhibitor of PIM (Proviral Integration site of Moloney murine leukemia virus) kinases with IC50 values of 0.24 nM, 30 nM and 0.12 nM for PIM1, PIM2 and PIM3 respectively in biochemical assays.

INCB053914 is a novel, potent, selective, and ATP-competitive small molecule pan-inhibitor of PIM (Proviral Integration site of Moloney murine leukemia virus) kinases with IC50 values of 0.24 nM, 30 nM and 0.12 nM for PIM1, PIM2 and PIM3 respectively in biochemical assays.

TP-3654 is a novel and potent inhibitor of Pim-1 and Pim-3 (proviral integration site for moloney murine leukemia virus) kinase that is potentially useful for the treatment of various cancers such as prostate cancer, acute myeloid leukemia, multiple sclerosis and psoriasis.

PIM447 2HCl (also known as LGH447 dihydrochloride), the dihydrochloride salt of PIM447, is a novel and potent pan-PIM (proviral insertion site of Moloney murine leukemia) kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively.

AZD1208 hydrochloride is a novel, potent, highly selective and orally bioavailable small molecule pan-inhibitor of Pim kinase with IC50 of 0.4 nM, 5 nM, and 1.9 nM for Pim1, Pim2, and Pim3 in cell-free assays, respectively.

NSC-31205 is a novel and potent inhibitor of PIM2/1.

Quercetagetin (6-Hydroxyquercetin) is a naturally occurring flavonoid and the major component isolated from Citrus unshiu (C. unshiu) peel, with anti-inflammatory and anticancer activity.

(1S,3R,5R)-PIM447 dihydrochloride a potent PIM inhibitor extracted with IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3.

Hispidulin is a novel and potent flavone.