3PO is a novel and potent inhibitor of the PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase)

PFK-015 (also known as PFK15) is a novel, potent and selective 6-phosphofructo-2-kinase (PFKFB3) inhibitor with IC50 of 207 nM.

3PO [full/chemical name of 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one] is an inhibitor of the PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase).

PFK-158 (formerly known as PFK158; ACT-PFK-158) is a first-in-class, potent and selective inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) with potential anticancer activity.