LCH-7749944, formerly known as GNF-Pf-2356, is a novel and highly potent PAK4 inhibitor with an IC50 of 14.93 μM.

PF-03758309 (PF03758309; PF-3758309; PF 03758309; PF3758309), a pyrrolopyrazole analog, is a novel, potent, orally bioavailable, and ATP-competitive small molecule inhibitor of PAK4 (p21-activated kinase 4) with potential antineoplastic activity.

IPA-3 (IPA3; IPA 3) is a novel, potent, selective and non-ATP competitive PAK1 (p21-activated protein kinase 1) inhibitor with potential antitumor activity.

FRAX597 (FRAX-597; FRAX 597) is a novel, potent and ATP-competitive inhibitor of group I PAKs (p21-activated Kinases) with potential anticancer activity.

Hydrastine (beta-Hydrastine; l-Hydrastine) is a natural alkaloid present in Hydrastis canadensis and other plants of the ranunculaceae family.

FRAX486 is a novel and potent p21-activated kinase (PAK) inhibitor (IC50 are 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively).

LCH-7749944 (also known as GNF-PF-2356) is a novel and potent PAK4 inhibitor ( IC50 = 14.93 μM).

FRAX1036 (FRAX-1036; FRAX 1036) is a selective p21-activated kinase 1 (PAK1) inhibitor with potential anticancer activity.

NVS-PAK1-1 is a a specific allosteric PAK1 inhibitor discovered in a fragment-based screen.