Indophagolin is a novel and potent indoline-containing autophagy inhibitor with IC50 of 140 nM.

Lu AF27139 a novel rodent-active and CNS-penetrant P2X7 receptor antagonist, which is highly selective and potent against rat, mouse, and human forms of the receptors.

AZD9056 hydrochloride is a novel, potent, selective, orally bioavailable antagonist of P2X7 receptor which is an adenosine triphosphate (ATP)-gated cation channel expressed on a variety of cell types believed to play a role in inflammation.

GW-791343 3HCl, the trihydrochloride salt form of GW-791343 (GW791343) is a novel, potent P2X7 allosteric modulator that exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 with pIC50 of 6.9 – 7.2.

A-317491 sodium, the tri-sodium salt of A-317491, which is a selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, which inhibits calcium flux mediated by the receptors.

A-438079 HCl is a novel, potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.

RO-3 is potent, selective, orally active and brain penetrant antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor with pIC50 values are 7.0 and 5.9 respectively.

A-317491 is a selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, which inhibits calcium flux mediated by the receptors.

Gefapixant (also known as AF-219 and MK-7264) is a novel, potent, and orally bioactive P2X3 receptor (P2X3R) antagonist with antitussive effects, and may be used for chronic cough.