Vebicorvir (formerly ABI H0731) is a first generation and orally bioavailable core protein inhibitor with antiviral (HBV) activity

Trastuzumab deruxtecan (DS-8201a; fam-trastuzumab deruxtecan; Enhertu) is a novel, potent and next-generation antibody-drug conjugate (ADC) composed of a monoclonal anti-HER2 antibody and a topoisomerase I inhibitor, an exatecan derivative (DX-8951f). It is a medication used for the treatment of adults with unresectable (unable to be removed with surgery) or metastatic (when cancer cells spread to […]

(S,R,S)-AHPC-PEG3-NH2 is a novel and potent E3 ligase ligand-linker

PROTAC FKBP Degrader-3 is a novel and potent PROTAC

Bis-PEG-TFP ester (MW 5000) is a novel and potent PROTAC linker

DBCO-PEG12-NHS ester is a novel and potent PROTAC linker

Cholesteryl oleate is a novel and potent cholesteryl ester

Endothelial lipase inhibitor-1 is a novel and potent endothelial lipase inhibitor

GSK-J5 is an inactive and pyridine regio-isomer of GSK-J4 which is a a cell-permeable and histone demethylase JMJD3/UTX inhibitor

α2β1 Integrin Ligand Peptide is a novel and potent antagonist of collagen receptors