RCGD-423 is a modulator of gp130 signalling.

Apilimod is a novel and potent small molecular inhibitor of IL-12/IL-23 and has been evaluated in clinical trials for patients with Crohn’s disease or rheumatoid arthritis.

JTE-607 HCl, the hydrochloride of JTE607, is a potent inhibitor of inflammatory cytokine production with the potential for the treatment of systemic inflammatory response.

Diacerein ( Diacerhein; Diacetylrhein) is slow-acting medication which acts as a potent inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, it is indicated for osteoarthritis and chronic inflammatory arthritis.

EC330 is a leukemia inhibitory factor (LIF) inhibitor.

RP-54745 (RP 54745) is a novel amino-dithiole-one compound that is active at micromolar concentration on the metabolism of stimulated macrophages, for example, the hexose monophosphate pathway (HMP) and the exocytosis of lysosomal enzymes.

Eupafolin is a novel and potent flavonoid.

YM-90709 is a novel antagonist of interleukin-5 receptor which inhibits the binding of interleukin-5 to interleukin-5 receptor.

GIBH-130 is a neuroinflammation inhibitor.

Apilimod mesylate, the mesylate salt of Apilimod, is a novel and potent small molecular inhibitor of IL-12/IL-23 and has been evaluated in clinical trials for patients with Crohn’s disease or rheumatoid arthritis.