Mildronate (Quaterin; Meldonium; Kvaterin; Mildronate), a structural analogue of gammabutyrobetaine and performance-enhancing drug developed by Latvia Institute of Organic Synthesis, is a potent inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase, also a competitive inhibitor of renal carnitine reabsorption.

Nepicastat HCl (SYN-117; SYN 117; RS-25560-197; RS 25560-197), the hydrochloride salt of Nepicastat, is a potent and selective inhibitor of dopamine-β-hydroxylase (an enzyme that catalyzes the conversion of dopamine to norepinephrine) with the potential to treat CHF-congestive heart failure.

(R)-Nepicastat HCl (R-SYN117; R-SYN-117; R-RS-25560-198 HCl), the R-enantiomer of Nepicastat HCl (RS-25560-197; SYN117; SYN-117; RS25560197), is a selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylases (enzymes catalyzing the transformation of dopamine to norepinephrine) with the potential to treat congestive heart failure.

Ro 61-8048 (Ro-618048) is a novel, high-affinity, oral, potent and selective kynurenine hydroxylase inhibitor (IC50 = 37 nM) with anti-dyskinesia activity.

Tetrahydropapaverine HCl (also called Norlaudanosine HCl), the hydrochloride salt of Tetrahydropapaverine, is a papaverine analog and a neuromuscular blocking agent with neurotoxic effects on dopamine neurons.

Telotristat (formerly known as LP-778902; LP778902) is the active metabolite of LX1606 (LX-1606; Telotristat etiprate) which is an orally bioavailable and small-molecule inhibitor of tryptophan hydroxylase (TPH, IC50 = 0.028 μM) with potential antiserotonergic activity.

DMOG (also called dimethyloxaloylglycine) is a novel, potent and cell permeable antagonist of α-ketoglutarate cofactor and competitive inhibitor for HIF prolyl hydroxylase with neuro- and cardioprotective effects.

Isotretinoin (Accutane; Myorisan; Zenatane; 13-cis retinoic acid) is a topically used medication approved for the treatment of severe cystic acne.

Telotristat Etiprate (LX1606 etiprate; LX1032; LX-1032; LX-1606) is the hippurate salt of telotristat ethyl, which is a prodrug of Telotristat.