Tyrphostin AG 879 (AG-879), a tyrphostin compound, is novel multi-tyrosine kinase inhibitor with potential antitumor activity.

Mubritinib (formerly also known as TAK165; TAK-165) is a novel, potent, selective and investigational inhibitor of HER2/ErbB2 with potential anticancer activity.

Pertuzumab (also known as 2C4; trade name Perjeta) is a humanized monoclonal antibody that acts as a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer. Pertuzumab is used in combination with trastuzumab and docetaxel for the treatment of metastatic HER2-positive breast cancer; it also used in the same combination as a neoadjuvant […]