SB415286 is a novel, potent, selective, cell permeable and ATP-competitive GSK3α (glycogen synthase kinase-3alpha) inhibitor with potential anti-inflammatory activity.
IM-12, an indolylmaleimide analog, is a novel, potent, cell-permeable and selective inhibitor of GSK-3β (glycogen synthase kinase-3β) with potential neuroprotective effects.
CHIR-98014 (also known as CT-98024) is a novel, potent, reversible, cell-permeable inhibitor of GSK-3 (glycogen synthase kinase-3) with potential anti-diabetic activity.
Laduviglusib (CHIR99021; CHIR-99021) 3HCl, the trihydrochloride salt form of CHIR-99021 (also called CT99021 or CHIR-911), is a potent and orally bioavailable GSK-3α/β (glycogen synthase kinase 3α/β) inhibitor with IC50 of 10 nM/6.7 nM in cell-free assays; CHIR-99021 was proved to promote self-renewal and maintain pluripotency of both B6 and BALB/c ES cells via stabilizing the […]
CP21R7 (also known CP21) is a potent and highly selective GSK-3β inhibitor that can potently activate canonical Wnt signalling with IC(50) of 0.6nM for GSK-3β.
WAY-624687 is a GSK-3 inhibitor