AZD5904 is a novel, potent, orally bioavailable, irreversible inhibitor of human MPO (Myeloperoxidase) with an IC50 of 140 nM and with similar potency in mouse and rat.
PF-06282999 is a novel, potent and selective myeloperoxidase (MPO) inhibitor with the potential for the treatment of cardiovascular diseases.
Tinoridine HCl (also known as Y-3642 HCl), the hydrochloride of tinoridine (Y-3642), is a nonsteroidal anti-inflammatory drug (NSAID) that also has potent radical scavenger and antiperoxidative activity.
PF-1355 (also known as PF-06281355), a 2-thiouracil analog, is a novel, potent, selective and orally bioavailable mechanism-based MPO inhibitor used for treatment of vasculitic diseases.
MPO-IN-28 (Compound 28) is a myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM.