GPR40/FFAR1 modulator 1 is a novel and potent allosteric modulator of GPR40/FFAR1 (Gq-coupled free fatty acid receptor 1).

GW-1100 is a novel, potent and selective GPR40 antagonist with a pIC50 of 6.9.

GPR120 Agonist 2 is a potent and selective agonist of the GPR120 (G-protein coupled receptor) receptor.

Pinocembrin (DL-0108), the racemate of Pinocembrin, is a potent androgen receptor ligand with the potential for the treatment of acute stroke.

TUG-770 is a novel, highly potent agonist of free fatty acid receptor 1 (FFA1/GPR40) with EC50 of 6 nM for hFFA1.

TUG-891 is a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), which displays both potential opportunity and possible challenges to therapeutic agonism.

GSK137647A, a diarylsulfonamide analog, is a novel, potent and selective agonists of the free fatty acid receptor 4 (FFA4/GPR120) with pEC50 of 6.3, 6.2, and 6.1 for human, mouse and rat FFA4, respectively.

Vincamine is a peripheral vasodilator, that increases blood flow to the brain.

AMG 837 calcium hydrate is a novel, orally bioavailable and potent GPR40 agonist with EC50 of 13 nM and with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.

AR-420626 (AR 420626; AR420626) is a novel and potent allosteric agonist of FFA3 (GPR41) receptor (pEC50 value of 5.74) with the potential for the treatment of neurogenic diarrheal disorders by suppressing nAChR-mediated neural pathways.