FTI-2148, a RAS C-terminal mimetic, is a novel, potent and highly selective dual inhibitor of farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1) with IC50s of 1.4 nM and 1.7 μM, respectively.

BMS-214662 is a novel, potent and selective inhibitor of farnesyl transferase (FT) with potential antitumor activity and an IC50 of 1.35 nM.

L-778123 (L778123) hydrochloride is a novel and potent inhibitor of FPTase (Farnesyl:protein transferase) and GGPTase-I (geranylgeranyl:protein transferase type-I) (IC50 = 2 nM and 98 nM) with anticancer activity.

OSI754 (also known as CP-609754, CP-609,754, LNK-754) is a novel and potent farnesyltransferase inhibitor (TFI) that has potential anticancer activity.

ABT-100 (ABT100) is a novel and potent farnesyltransferase inhibitor with a broad-spectrum antitumor activity.