Edoxaban tosylate monohydrate (DU-176b; DU-176; trade name Lixiana), the tosylate salt of edoxaban which is a marketed anticoagulant drug, is a potent, selective, orally bioavailable and direct factor Xa inhibitor with potential anti-coagulant activity.
Apixaban (formerly BMS56224701; BMS 56224701; BMS-56224701; trade name: Eliquis), an approved drug used to treat and prevent the formation of blood clots, is a highly selective, reversible, direct inhibitor of Factor Xa with potential anti-coagulant activity.
Rivaroxaban (BAY59-7939; BAY-59-7939; trade name: Xarelto), an approved anticoagulant drug used to treat and prevent blood clots, is the first orally bioavailable, selective and direct inhibitor of Factor Xa with potential anti-coagulant activity.
Edoxaban (also known as DU-176b; DU176; Lixiana; Savaysa) is a potent, direct-acting, selective, orally bioavailable factor Xa inhibitor used as an anticoagulant drug.
Fondaparinux sodium (PENTA; SR-90107A; IC-85158; Arixtra; Xantidar) is a factor Xa inhibitor to form the high affinity binding site for the anti-coagulant factor antithrombin III (ATIII).
BMS-654457 is a novel, potent, reversible small-molecule inhibitor of factor XIa (FXIa), which binds to human and rabbit FXIa with Kis of 0.2 and 0.42 nM, respectively.
Edoxaban tosylate (DU176b; DU-176; trade name Savaysa; Lixiana), the tosylate salt of edoxaban, is a marketed anticoagulant drug acting as a potent, selective, orally bioavailable and direct factor Xa inhibitor.
Apixaban 13CD3, the deuterated form of Apixaban, is an internal standard (IS) extensively used for the quantification of apixaban which is a coagulation factor Xa inhibitor used to treat and prevent the formation of blood clots.
Betrixaban (trade name Bevyxxa; formerly PRT054021; MK-4448; PRT-021; MLN-1021 etc.) is a highly potent, selective, and orally bioavailalbe anticoagulant drug which acts as a direct factor Xa inhibitor.
5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban (also known as BAY 59-7939) which is the first orally available, direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively.